Intra Cytoplasmic Sperm Injection (ICSI)

Understanding ICSI

In about 40% of cases fertilisation would not occur if the sperm and eggs were placed together as in regular IVF.  To overcome this, a technique of injecting an individual sperm into the centre of the egg has been developed called Intra-Cytoplasmic Sperm Injection (ICSI) .  This technique is carried out by the embryologist using a microscope under high magnification.

There are various indications for carrying out ICSI during IVF treatment. These factors fall broadly into the following groups, however a combination of these is often seen:

  • Low sperm number (oligozoospermia)
  • Reduced motility or survival of the sperm (asthenozoospermia)
  • Low numbers of normal shaped sperm in the sample (teratozoospermia)
  • Sperm retrieved from a testicular biopsy
  • A high level of antisperm antibodies in the male partner
  • Egg abnormailities
  • Unexpected failure to fertilise in a previous IVF treatment cycle



Steps involved in ICSI

ICSI is similar to IVF; however 1 additional step is added to the process. The following steps apply:

  1. Stimulation of the ovaries
  2. Egg Collection
  3. ICSI Procedure – injection of a single sperm directly into the egg. 
  4. Fertilisation of the eggs and culture of the embryos
  5. Embryo Transfer

What is the Success rate for ICSI?

Galway Fertility Clinic has an average positive pregnancy rate of 40% and a take home baby rate of 30%, per ICSI treatment cycle.

Chances of a successful outcome depend primarily on the woman’s age, declining significantly after 41 years of age.