Galway Fertility Clinic is delighted to announce that Preimplantation Genetic Testing (PGT) is now available, following approval by the Health Products Regulatory Authority (HPRA).
This test is especially beneficial to patients experiencing repeated failed embryo implantation or miscarriage, as it gives our laboratory the ability to identify the embryos with the best potential to develop into healthy babies.
PGT is designed to test your embryos for chromosomal abnormalities before they are transferred into the womb. This significantly increases your chance of pregnancy and reduces your risk of miscarriage.
Before PGT was available, embryo selection was based on morphology and development, which essentially means how the embryos look and grow. But what we couldn’t tell was – what was inside the embryo, its number of chromosomes.
Normally we inherit one set of 23 chromosomes from mum (the egg) and one set of 23 chromosomes from dad (the sperm), leaving us with a full complement of 46 chromosomes. But, just by looking down the microscope an embryo could appear to be good quality based on its morphology and development, but inside it could be chromosomally abnormal.
All couples can potentially create chromosomally abnormal embryos, contributed either from the sperm or the egg. But this risk significantly increases with increasing female age. At 35 years of age, a woman has around 30% risk of creating chromosomally abnormal embryos, but by 40 years old this risk increases to almost 70%. This chromosomal abnormality is a major factor in failed IVF cycles, and a major factor in miscarriages. PGT testing may be most beneficial if this is relevant to you.
The majority of the time, if embryos are chromosomally abnormal, they simply do not implant into the womb, failing to achieve a pregnancy month after month. Although, in some cases, chromosomally abnormal embryos implant and result in miscarriage, or the birth of a baby with genetic abnormalities.
But now, using PGT, we are able to extract a tiny sample of cells from the individual embryos which are then tested for the correct number of chromosomes. The embryos are then frozen until the results are ready and an embryo with the correct chromosome number can then be selected and transferred into your uterus. These tested embryos have a higher chance of implanting, allowing you to take home a healthy baby.
For more information about our PGT program please click here to contact us and arrange an appointment with one of our consultants, who will assess whether PGT is a suitable option for you.